Modified Gegen Qinlian decoction ameliorates DSS-induced chronic colitis in mice by restoring the intestinal mucus barrier and inhibiting the activation of Î³Î´T17 cells.

Ma, Jing; Zhang, Jiaqi; Wang, Yifan; Huang, Jinke; Yang, Xuefei; Ma, Jinxin; Liu, Zhihong; Wang, Fengyun; Tang, Xudong

Ma, Jing; Zhang, Jiaqi; Wang, Yifan; Huang, Jinke; Yang, Xuefei; Ma, Jinxin; Liu, Zhihong; Wang, Fengyun; Tang, Xudong.

Afiliación

Ma J; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Zhang J; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Wang Y; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Huang J; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Yang X; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Ma J; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Liu Z; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Wang F; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Tang X; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: txdly@sina.com.

Phytomedicine ; 111: 154660, 2023 Mar.

Article en En | MEDLINE | ID: mdl-36681051

Asunto(s)

Colitis Ulcerosa; Colitis; Animales; Ratones; Colitis/inducido químicamente; Colitis/tratamiento farmacológico; Colitis Ulcerosa/inducido químicamente; Colitis Ulcerosa/tratamiento farmacológico; Colitis Ulcerosa/metabolismo; Colon/patología; Sulfato de Dextran/toxicidad; Modelos Animales de Enfermedad; Inflamasomas/metabolismo; Ratones Endogámicos C57BL; Moco; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo

Palabras clave

Modified Gegen Qinlian decoction; NLRP3 inflammasome; Ulcerative colitis; Î³Î´T17 cells

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Colitis Tipo de estudio: Prognostic_studies Idioma: En Revista: Phytomedicine Año: 2023 Tipo del documento: Article País de afiliación: China

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