Quercetin extraction from small onion skin (Allium cepa L. var. aggregatum Don.) and its antioxidant activity.
Environ Res
; 224: 115497, 2023 05 01.
Article
en En
| MEDLINE
| ID: mdl-36805894
ABSTRACT
In the present study, the maximum yield of quercetin was optimized for the ethanol extraction of small onions (Allium cepa L. var. aggregatum Don.), and the antioxidant activity was investigated in vitro. The extraction of quercetin from the small onion skin was carried out through ethanol solvent extraction with different ratios of ethanol and water. Ethanol water ratio produced the highest quercetin from the onion skin. RP-HPLC analysis of the extracted material showed 2, 122 mg/g of quercetin and 0.34 mg/g of isorhamnetin. A total of 301.03 mg GAE/g dry weight and 156 mg/g quercetin equivalents were found in the onion skin extract. DPPH and ABTS free radical scavenging potentials of the tested extract (9010 v/v) were dose-dependent, with IC50 values of 62.27 µg/mL and 53.65 µg/mL, respectively. Therefore, the present study reports that small onion skin extract rich in quercetin may serve as a promising antioxidant and anticancer agent.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Medicinas Complementárias:
Homeopatia
Asunto principal:
Quercetina
/
Chalotes
Idioma:
En
Revista:
Environ Res
Año:
2023
Tipo del documento:
Article