A-H, Alpers-Huttenlocher syndrome; AD, Alzheimer's disease; ALS, Amyotrophic lateral sclerosis; BBB, blood-brain barrier; C. elegans,, Caenorhabditis elegans; CJD, Creutzfeldt-Jakob disease; CMT, Charcot­Marie­Tooth disease; CS, Cockayne syndrome; Ech A, Echinochrome A; FDA, Food and Drug Administration; FRDA, Friedreich's ataxia; FTD, Frontotemporal dementia; HD, Huntington's disease; Hsp, Heat shock protein; LSD, Lysosomal storage diseases; MS, Multiple sclerosis; MSA, Multiple system atrophy; MSP, Multisystem proteinopathy; Medicinal plant; ND, neurodegenerative disease; NPC, Neimann-Pick disease type C; NSC, neural stem cells; Neuro-inflammation; Neurodegeneration; Neurogenesis; PC, pharmacological chaperone; PD, Parkinson's disease; Protein misfolding; SMA, Spinal muscular atrophy; VD, Vascular dementia; prion dis, prion diseases; α-syn, alpha-synuclein