Berberine activates PPARÎ´ and promotes gut microbiota-derived butyric acid to suppress hepatocellular carcinoma.

Shou, Jia-Wen; Shaw, Pang-Chui

Shou, Jia-Wen; Shaw, Pang-Chui.

Afiliación

Shou JW; Li Dak Sum Yip Yio Chin R&D Centre for Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Shaw PC; Li Dak Sum Yip Yio Chin R&D Centre for Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China; State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants and Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: pcshaw@cuhk.edu.hk.

Phytomedicine ; 115: 154842, 2023 Jul.

Article en En | MEDLINE | ID: mdl-37148713

Asunto(s)

Berberina; Carcinoma Hepatocelular; Microbioma Gastrointestinal; Neoplasias Hepáticas; PPAR delta; Ratones; Animales; Carcinoma Hepatocelular/tratamiento farmacológico; PPAR delta/farmacología; Ácido Butírico/farmacología; Berberina/farmacología; Caspasa 3; Proteína X Asociada a bcl-2; Neoplasias Hepáticas/tratamiento farmacológico

Palabras clave

Berberine; Butyrate; Gut microbiota-liver axis; Hepatocellular carcinoma; PPARÎ´

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Berberina / Carcinoma Hepatocelular / PPAR delta / Microbioma Gastrointestinal / Neoplasias Hepáticas Idioma: En Revista: Phytomedicine Año: 2023 Tipo del documento: Article País de afiliación: China

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