c-Myc protects hepatocellular carcinoma cell from ferroptosis induced by glutamine deprivation via upregulating GOT1 and Nrf2.

Zhao, Yuxiang; Wang, Yue; Miao, Zeyu; Liu, Yan; Yang, Qing

Zhao, Yuxiang; Wang, Yue; Miao, Zeyu; Liu, Yan; Yang, Qing.

Afiliación

Zhao Y; Department of Pathogenobiology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Street, Changchun, 130021, Jilin Province, China.
Wang Y; Department of Pathogenobiology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Street, Changchun, 130021, Jilin Province, China.
Miao Z; Department of Pathogenobiology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Street, Changchun, 130021, Jilin Province, China.
Liu Y; Department of Pathogenobiology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Street, Changchun, 130021, Jilin Province, China.
Yang Q; Department of Pathogenobiology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Street, Changchun, 130021, Jilin Province, China. yangq@jlu.edu.cn.

Mol Biol Rep ; 50(8): 6627-6641, 2023 Aug.

Article en En | MEDLINE | ID: mdl-37358765

Asunto(s)

Carcinoma Hepatocelular; Ferroptosis; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/metabolismo; Aspartato Aminotransferasa Citoplasmática/metabolismo; Aspartato Aminotransferasa Citoplasmática/uso terapéutico; Neoplasias Hepáticas/metabolismo; Factor 2 Relacionado con NF-E2/genética; Glutamina/farmacología; Glutamina/metabolismo; Línea Celular Tumoral

Palabras clave

Ferroptosis; GOT1; Glutamine deprivation; Hepatocellular carcinoma; c-Myc

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Ferroptosis / Neoplasias Hepáticas Idioma: En Revista: Mol Biol Rep Año: 2023 Tipo del documento: Article País de afiliación: China

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