Photosensitization of leukemia L1210 cells with diaziquone.
Cancer Res
; 46(11): 5587-8, 1986 Nov.
Article
en En
| MEDLINE
| ID: mdl-3756904
ABSTRACT
Exposure of leukemia L1210 cells in culture to the drug diaziquone resulted in inhibition of incorporation of labeled thymidine into nucleic acid and loss of cell viability. These effects were markedly potentiated by irradiation of cells previously exposed to diaziquone in culture. This result shows that diaziquone can catalyze phototoxicity; the action spectrum of the drug may limit clinical applications of this phenomenon.
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Bases de datos:
MEDLINE
Asunto principal:
Fototerapia
/
Aziridinas
/
Azirinas
/
Leucemia L1210
/
Benzoquinonas
Idioma:
En
Revista:
Cancer Res
Año:
1986
Tipo del documento:
Article