Ayanin, a natural flavonoid inhibitor of Caseinolytic protease, is a promising therapeutic agent to combat methicillin-resistant Staphylococcus aureus infections.

Jin, Mengli; Zhu, Shuyue; Tang, Yating; Kong, Xiangri; Wang, Xingye; Li, Yufen; Jiang, Shuang; Wei, Lin; Hu, Chunjie; Wang, Bingmei; Song, Wu

Jin, Mengli; Zhu, Shuyue; Tang, Yating; Kong, Xiangri; Wang, Xingye; Li, Yufen; Jiang, Shuang; Wei, Lin; Hu, Chunjie; Wang, Bingmei; Song, Wu.

Afiliación

Jin M; Changchun University of Chinese Medicine, Changchun 130117, China.
Zhu S; Changchun University of Chinese Medicine, Changchun 130117, China.
Tang Y; Changchun University of Chinese Medicine, Changchun 130117, China.
Kong X; Changchun University of Chinese Medicine, Changchun 130117, China.
Wang X; Changchun University of Chinese Medicine, Changchun 130117, China.
Li Y; Changchun University of Chinese Medicine, Changchun 130117, China.
Jiang S; Changchun University of Chinese Medicine, Changchun 130117, China.
Wei L; Changchun University of Chinese Medicine, Changchun 130117, China.
Hu C; Changchun University of Chinese Medicine, Changchun 130117, China; Proctology Department, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China. Electronic address: 1224264871@qq.com.
Wang B; Changchun University of Chinese Medicine, Changchun 130117, China. Electronic address: bingmeiwang1970@163.com.
Song W; Changchun University of Chinese Medicine, Changchun 130117, China. Electronic address: songwu@ccucm.edu.cn.

Biochem Pharmacol ; 217: 115814, 2023 11.

Article en En | MEDLINE | ID: mdl-37769713

Asunto(s)

Staphylococcus aureus Resistente a Meticilina; Infecciones Estafilocócicas; Animales; Ratones; Staphylococcus aureus; Péptido Hidrolasas/farmacología; Simulación del Acoplamiento Molecular; Flavonoides/farmacología; Flavonoides/uso terapéutico; Infecciones Estafilocócicas/tratamiento farmacológico; Factores de Virulencia; Endopeptidasas; Antibacterianos/farmacología; Antibacterianos/uso terapéutico; Pruebas de Sensibilidad Microbiana

Palabras clave

Anti-virulence; Ayanin; Caseinolytic protease (ClpP); Methicillin-resistant; Staphylococcus aureus (S. aureus); Vancomycin

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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Plantas_medicinales Asunto principal: Infecciones Estafilocócicas / Staphylococcus aureus Resistente a Meticilina Idioma: En Revista: Biochem Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: China

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