The protective effects of curcumin against cigarette smoke-induced toxicity: A comprehensive review.
Phytother Res
; 38(1): 98-116, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-37813398
ABSTRACT
Cigarette smoking (CS) is a crucial modifiable risk of developing several human diseases and cancers. It causes lung, bladder, breast, and esophageal cancers, respiratory disorders, as well as cardiovascular and metabolic diseases. Because of these adverse health effects, continual efforts to decrease the prevalence and toxicity of CS are imperative. Until the past decades, the impacts of natural compounds have been under investigation on the harmful effects of CS. Turmeric (Curcuma longa), a rhizomatous herbaceous perennial plant that belongs to the Zingiberaceae family, is the main source of curcumin. This review is an attempt to find out the current knowledge on CS's harmful effects and protective potential of curcumin in the pulmonary, liver, brain, gastrointestinal, and testis organs. According to the present review, simultaneous consumption of curcumin and CS can attenuate CS toxicities including chronic obstructive pulmonary disease, gastrointestinal toxicity, metabolic diseases, testis injury, and neurotoxicity. Moreover, curcumin suppresses carcinogenesis in the skin, liver, lungs, breast, colon, and stomach. Curcumin mediates these protective effects through antioxidant, anti-inflammatory, anti-apoptotic, and anti-carcinogenicity properties.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Curcumina
/
Fumar Cigarrillos
/
Enfermedades Metabólicas
Tipo de estudio:
Risk_factors_studies
Idioma:
En
Revista:
Phytother Res
Año:
2024
Tipo del documento:
Article
País de afiliación:
Irán