Catalpol rescues LPS-induced cognitive impairment via inhibition of NF-&#922;b-regulated neuroinflammation and up-regulation of TrkB-mediated BDNF secretion in mice.

Hu, Weiqing; Zou, Li; Yu, Ningxi; Wu, Zhizhongbin; Yang, Wei; Wu, Tianyue; Liu, Yulin; Pu, Yu; Jiang, Yunbing; Zhang, Jifeng; Zhu, Huifeng; Cheng, Fang; Feng, Shan

Catalpol rescues LPS-induced cognitive impairment via inhibition of NF-Κb-regulated neuroinflammation and up-regulation of TrkB-mediated BDNF secretion in mice.

Hu, Weiqing; Zou, Li; Yu, Ningxi; Wu, Zhizhongbin; Yang, Wei; Wu, Tianyue; Liu, Yulin; Pu, Yu; Jiang, Yunbing; Zhang, Jifeng; Zhu, Huifeng; Cheng, Fang; Feng, Shan.

Afiliación

Hu W; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: huweiqing1415@163.com.
Zou L; Sichuan Vocational College of Health and Rehabilitation, Zigong, 643000, China. Electronic address: zxm18611@163.com.
Yu N; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: 18086610815@163.com.
Wu Z; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: wuzhizhongbin@163.com.
Yang W; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: yw2741816442@163.com.
Wu T; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: 15723261709@163.com.
Liu Y; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: 1579454430@qq.com.
Pu Y; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: 2650376189@qq.com.
Jiang Y; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: yunbinjiang@swu.edu.cn.
Zhang J; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China.
Zhu H; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: zhfbsci@126.com.
Cheng F; The Third Affiliated Hospital of Henan University of Chinese Medicine, 63 Dongming Road, Zhengzhou City, Henan Province, China. Electronic address: cfzy119@163.com.
Feng S; Department of Traditional Chinese Medicine, College of Pharmaceutical Sciences and Traditional Chinese Medicine, Southwest University, Chongqing, 400715, China. Electronic address: fengshan@swu.edu.cn.

J Ethnopharmacol ; 319(Pt 3): 117345, 2024 Jan 30.

Article en En | MEDLINE | ID: mdl-37926114

Asunto(s)

Disfunción Cognitiva; Sepsis; Ratas; Animales; Ratones; FN-kappa B; Regulación hacia Arriba; Factor Neurotrófico Derivado del Encéfalo; Lipopolisacáridos/toxicidad; Cromatografía Liquida; Simulación del Acoplamiento Molecular; Enfermedades Neuroinflamatorias; Espectrometría de Masas en Tándem; Disfunción Cognitiva/tratamiento farmacológico

Palabras clave

Catalpol; Neuroinflammation; Septic-associated encephalopathy; TrkB

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sepsis / Disfunción Cognitiva Idioma: En Revista: J Ethnopharmacol Año: 2024 Tipo del documento: Article