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Discovery of novel dual Bruton's tyrosine kinase (BTK) and Janus kinase 3 (JAK3) inhibitors as a promising strategy for rheumatoid arthritis.
Liang, Tingting; Cen, Lifang; Wang, Junjie; Cheng, Ming; Guo, Weibo; Wang, Wenjie; Yu, Chunqiu; Zhang, Haifeng; Wang, Yuan; Hao, Zhongyan; Jin, Jiaming; Wu, Yaoyao; Jiang, Teng; Zhu, Qihua; Xu, Yungen.
Afiliación
  • Liang T; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Cen L; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Wang J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Cheng M; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Guo W; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Wang W; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Yu C; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Zhang H; Xi'an Xintong Pharmaceutical Research Co., Ltd. Xian, 710077, China.
  • Wang Y; Xi'an Xintong Pharmaceutical Research Co., Ltd. Xian, 710077, China.
  • Hao Z; Xi'an Xintong Pharmaceutical Research Co., Ltd. Xian, 710077, China.
  • Jin J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Wu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China.
  • Jiang T; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Zhu Q; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
  • Xu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. Electronic address: xyg@cpu.edu.cn.
Bioorg Med Chem ; 96: 117354, 2023 12 15.
Article en En | MEDLINE | ID: mdl-37944414
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Artritis Reumatoide / Inhibidores de las Cinasas Janus Idioma: En Revista: Bioorg Med Chem Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Artritis Reumatoide / Inhibidores de las Cinasas Janus Idioma: En Revista: Bioorg Med Chem Año: 2023 Tipo del documento: Article País de afiliación: China