Ligustilide prevents thymic immune senescence by regulating Thymosin ß15-dependent spatial distribution of thymic epithelial cells.

Xu, Xie; Tao, Nana; Sun, Caihua; Hoffman, Robert D; Shi, Dongling; Ying, Yuyuan; Dong, Shujie; Gao, Jianli

Xu, Xie; Tao, Nana; Sun, Caihua; Hoffman, Robert D; Shi, Dongling; Ying, Yuyuan; Dong, Shujie; Gao, Jianli.

Afiliación

Xu X; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; Zhejiang Provincial Hospital of Chinese Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China. Electronic address: 516905925@qq.com.
Tao N; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China. Electronic address: 202111124011114@zcmu.edu.cn.
Sun C; Zhejiang Provincial Hospital of Chinese Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China. Electronic address: sch.szyy@163.com.
Hoffman RD; Yo San University of Traditional Chinese Medicine, Los Angeles, CA 90066, USA. Electronic address: rhoffman@yosan.edu.
Shi D; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang, China. Electronic address: 1183726327@qq.com.
Ying Y; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China. Electronic address: 202111124011129@zcmu.edu.cn.
Dong S; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China. Electronic address: 202111114011074@zcmu.edu.cn.
Gao J; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao 999078, China. Electronic address: jianligao@zcmu.edu.cn.

Phytomedicine ; 123: 155216, 2024 Jan.

Article en En | MEDLINE | ID: mdl-38061285

Asunto(s)

4-Butirolactona/análogos & derivados; Actinas; Timosina; Ratones; Animales; Actinas/metabolismo; Timosina/farmacología; Timosina/metabolismo; Simulación del Acoplamiento Molecular; Células Epiteliales

Palabras clave

Immune senescence; Ligustilide; Spatial development; Thymic epithelial cells; Thymosin ß15

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Timosina / 4-Butirolactona / Actinas Idioma: En Revista: Phytomedicine Año: 2024 Tipo del documento: Article