Impact of internal metal ions in tea polysaccharides on antioxidant potential and suppression of cancer cell growth.
Fitoterapia
; 173: 105786, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38135093
ABSTRACT
Four kinds of tea polysaccharides (MBTPS, MGTPS, ZBTPS, ZGTPS) were extracted from Maofeng black tea, Maofeng green tea,Ziyan black tea and Ziyan green tea, and then four tea polysaccharides (RMBTPS, RMGTPS, RZBTPS, RZGTPS) after metal removal were prepared. The physicochemical properties, antioxidant activity and inhibitory activity on cancer cell proliferation of the above polysaccharides were studied. The composition analysis shows that these tea polysaccharides were glycoproteins complexes, composed of a variety of monosaccharides, and the removal of metal ions did not lead to fundamental changes in the composition of polysaccharides. In vitro activity, after removing metal ions, the ABTS free radicals scavenging ability and reducing power of tea polysaccharides were decreased, and the inhibitory effect on proliferation of H22 cells weakened. There was a great correlation between metal elements Al and Ni and biological activity. The results showed that the metal ions in tea polysaccharides, especially Al and Ni, had positive effects on biological activity.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias
/
Antioxidantes
Idioma:
En
Revista:
Fitoterapia
Año:
2024
Tipo del documento:
Article
País de afiliación:
China