[Study on allergen components of birch pollen in Beijing area].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
; 38(3): 195-199, 2024 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-38433686
ABSTRACT
Objective:
To explore the allergen components of birch pollen in the Beijing area and interpret its clinical significance.Methods:
A total of 58 patients with birch pollen allergy were included in the cross-sectional study and divided into allergic rhinitisï¼ARï¼ and allergic asthmaï¼AAï¼ groups according to clinical manifestations. Concentration of birch pollen allergen sIgE, as well as Bet v 1, Bet v 2, Bet v 4 and Bet v 6 sIgE were detected by ImmunoCAP immunolinked immunoassay. Differences of sIgE concentration of birch pollen allergen component in AR and AA were analyzed.Results:
There were 44ï¼75.9%ï¼ cases of AR and 14ï¼24.1%ï¼ cases of AA were enrolled. All the 18 patients with spring pollen allergy were AR patients without AA. There were 40 cases with both spring and autumn pollen allergy, of which 26 casesï¼65%ï¼ were AR and 14 casesï¼35%ï¼ were AA. The sIgE of birch pollen allergen was level 2 or above in all subjects. 94.8% were positive for any four allergen components. 77.6% were mono-sensitized to any allergen component while 17.2% were dual-sensitized. The positive rate of Bet v 1 and/or Bet v 2 was 93.1%. The positive rates of four protein components were Bet v 1ï¼82.8%ï¼, Bet v 2ï¼29.3%ï¼, Bet v 6ï¼1.7%ï¼, Bet v 4ï¼0%ï¼. sIgE of birch pollen was positively correlated with sIgE level of Betv 1ï¼r=0.898, P<0.001ï¼. The sIgE concentration of Bet v2 in AA group was significantly higher than that in AR groupï¼[4.34±14.35] kUA/L vs [1.56±3.26] kUA/L, P<0.05ï¼. There was no significant difference in other components.Conclusion:
Bet v 1 is the main allergen component of birch pollen in the Beijing area, and Bet v 1 plus Bet v 2 can diagnose more than 90% of birch pollen allergy.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Rinitis Alérgica Estacional
/
Rinitis Alérgica
Idioma:
Zh
Revista:
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
/
Lin chuang er bi yan hou tou jing wai ke za zhi
Año:
2024
Tipo del documento:
Article