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Ten cyclopentanoid monoterpenes from the whole plant of Rehmannia piasezkii maxim.
Zhou, Jie; Shi, Guoru; Zhang, Wanqi; Chen, Ruoyun; Yu, Shishan; Yu, Dequan; Liu, Yanfei.
Afiliación
  • Zhou J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Shi G; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Zhang W; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Chen R; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Yu S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: yushishan@imm.ac.cn.
  • Yu D; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Liu Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: catalpol@imm.ac.cn.
Fitoterapia ; 175: 105968, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38636908
ABSTRACT
Ten new cyclopentanoid monoterpenes (1-10) were isolated from the whole plant of Rehmannia piasezkii. The structures of these compounds were elucidated based on spectroscopic data analysis. In in-vitro assays, compounds 3, 7, and 9 exhibited weak hepatoprotective activities against APAP-induced HepG2 cell damage. Compound 9 exhibited protective effect on hapassocin carbon tetrachloride model.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Rehmannia / Monoterpenos / Fitoquímicos País/Región como asunto: Asia Idioma: En Revista: Fitoterapia Año: 2024 Tipo del documento: Article País de afiliación: China
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Rehmannia / Monoterpenos / Fitoquímicos País/Región como asunto: Asia Idioma: En Revista: Fitoterapia Año: 2024 Tipo del documento: Article País de afiliación: China