[Treatment of severe febrile neutropenia (author's transl)]. / Zur Behandlung der schweren febrilen Neutropenie.
Dtsch Med Wochenschr
; 105(51): 1776-9, 1980 Dec 19.
Article
en De
| MEDLINE
| ID: mdl-6449360
ABSTRACT
Random allocation of 22 patients with benign and malignant diseases with neutrophil counts of up to 1 X 10(9)/l blood and probably infection-caused fever of more than 38 degrees C to intravenous treatment with one of the following antibiotic combinations was performed carbenicillin (6 g/m(2) . 6 h) plus sisomicin (45 g/m2 . 6 h) or mezlocillin (3 g/m2 . 6 h) plus sisomicin (45 g/m2 . 6 h). Both combinations were tolerated equally well. Patients became afebrile in 16 out of 23 treatment periods. Seven out of 11 patients responded to carbenicillin - sisomicin, and 9 out of 12 to mezlocillin - sisomicin. Mezlocillin thus leads to equal success of treatment in febrile neutropenia as the double dose of carbenicillin when both antibiotics are combined with the same aminoglycoside.
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Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
/
Aromoterapia
Asunto principal:
Penicilinas
/
Carbenicilina
/
Gentamicinas
/
Sisomicina
/
Agranulocitosis
/
Neutropenia
Tipo de estudio:
Clinical_trials
/
Etiology_studies
Idioma:
De
Revista:
Dtsch Med Wochenschr
Año:
1980
Tipo del documento:
Article