Membrane fusion mediated by ricin and viscumin.
Biochim Biophys Acta
; 1371(1): 11-6, 1998 Apr 22.
Article
en En
| MEDLINE
| ID: mdl-9565651
The ribosome inactivating plant proteins (RIPs) ricin and viscumin but not Ricinus communis agglutinin are able induce vesicle-vesicle fusion. A model is suggested in which the toxicity of the RIPs is partially determined by their fusogenicity. Herein, fusion is hypothesized to allow the RIPs to leak across endocytic vesicles to approve their access to cytoplasmic ribosomes.
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Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Proteínas de Plantas
/
Ricina
/
Toxinas Biológicas
/
Preparaciones de Plantas
/
Fusión de Membrana
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
1998
Tipo del documento:
Article
País de afiliación:
Alemania