The effect of shourong compound formula on levels of dopamine and its metabolites in brain of Parkinson's disease mice induced by reserpine / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 368-370, 2002.
Article
en Zh
| WPRIM
| ID: wpr-263658
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of Shourong compound formula on treating Parkinson's disease.</p><p><b>METHOD</b>Parkinson's disease model mice induced by reserpine was used and by HPLC-ED the levels of Dopamine (DA) and its metabolites were determined.</p><p><b>RESULT</b>Madopar could increase the levels of DA in brain of PD mice. The effect of madopar together with Sourong compound formula was better than that of madopar(P < 0.001).</p><p><b>CONCLUSION</b>Shourong compound formula together with madopar has synergic effect on increase of DA level in brain and can reduce clinic dose of madopar so that side effect of madopar can be decreased.</p>
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Enfermedad de Parkinson Secundaria
/
Farmacología
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Plantas Medicinales
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Reserpina
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Encéfalo
/
Ácido 3,4-Dihidroxifenilacético
/
Medicamentos Herbarios Chinos
/
Extractos Vegetales
/
Benserazida
/
Dopamina
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2002
Tipo del documento:
Article