Study on antiinflammatory effect of a compound TCM agent containing ant extractive in animal models / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 215-218, 2002.
Article
en Zh
| WPRIM
| ID: wpr-274978
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the antiinflammatory effect of a compound TCM (Traditional Chinese Medicine) agent on animal models. The agent contains ant extractive and a blent of three herbal products, herba epimedii, fructus cnidii, and fructus lycii.</p><p><b>METHOD</b>Three animal models to induce experimental inflammation in rats, including carrageenin--induced paw edema, cotton-ball granuloma and adjuvant induced arthritis, were chosen to study the antiinflammatory effect of the TCM agent.</p><p><b>RESULT</b>The TCM agent showed a marked inhibitory effect on edema induced by all three types of inflammation in rats, the inhibitory rate of the TCM agent at the dose of 0.20, 0.40 and 0.80 g.kg-1 in granuloma model bing over 25% at 1 hour post oral administration, and being 23.8%, 22.7%, 39.7% at 6 hour. In addition, the TCM agent also showed a significant preventive as well as therapeutic effect on adjuvant induced arthritis in rats, and improved the pathological changes of the animal joints with the induced arthritis.</p><p><b>CONCLUSION</b>TCM agent has significant antiinflammatory effects on the three above mentioned animal models.</p>
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Medicinas Complementárias:
Homeopatia
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Hormigas
/
Plantas Medicinales
/
Artritis
/
Cápsulas
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Medicamentos Herbarios Chinos
/
Materia Medica
/
Granuloma de Cuerpo Extraño
/
Química
/
Antiinflamatorios no Esteroideos
/
Ratas Wistar
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2002
Tipo del documento:
Article