Genotoxicity research thought and method on traditional Chinese medicine / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2696-2700, 2015.
Article
en Zh
| WPRIM
| ID: wpr-337906
Biblioteca responsable:
WPRO
ABSTRACT
Genotoxicity research takes an important place in traditional Chinese medicine safety evaluation. Genotoxicity test on traditional Chinese medicine has been paid great attention since 1970s. Currently, the most developed genotoxicity test methods included bacterial reverse mutation test and mouse lymphoma assay which are used to detect relevant genetic changes, micronucleus test and chromosomal analysis which are used to measure chromosomal aberration, and single cell electrophoresis assay which is used to test DNA damage. This article reviews research progress on genotoxicity of traditional Chinese medicine, evaluation methods of genotoxicity, the problems and solutions on genotoxicity evaluation of traditional Chinese medicine, and new technique used in genotoxicity test.
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Asunto principal:
Investigación Biomédica
/
Medicina Tradicional China
/
Métodos
/
Pruebas de Mutagenicidad
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2015
Tipo del documento:
Article