Effect of electroacupuncture combined with medication on vascular endothelial cells in the compound hypertension and hyperlipemia rat / 中国针灸
Chinese Acupuncture & Moxibustion
; (12): 875-878, 2006.
Article
en Zh
| WPRIM
| ID: wpr-348416
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the mechanism of electroacupuncture combined with medication for treatment of compound model of hypertension and hyperlipemia (CMHH).</p><p><b>METHODS</b>CMHH rat model was made by the way of "2K1C" combined with intragastric perfusion of high fat diet, and a normal group and a pseudosurgery group were set up. After modeling for 4 weeks, the successful model rats who had synchronously increase of blood pressure (BP) and blood lipids were randomly divided into a model group, a medication group , an electroacupuncture group and an acupuncture plus medication group. After interference of 4 weeks, changes of BP, total cholesterol (TC) and thiglyceride (TG) and contents of serum vWF, tissue plasminogen activator (t-PA ) and plasminogen activator inhibitor-1 (PAl-1) were observed.</p><p><b>RESULTS</b>After interference, the levels of BP, TC, TG, vWF, t-PA and PAl-1 significantly changed in all the treatment groups as compared with those in the model group (P < 0.05 or P < 0.01) with most significantly changed in the electroacupuncture plus medication group.</p><p><b>CONCLUSION</b>Both electroacupunctore and electroacupuncture combined with medication can down-regulate levels of BP, TC, TG, and decrease plasma vWF and PAl-1 levels, increase t-PA content, so as to effectively prevent and treat CMHH and possibly induced cerebral diseases.</p>
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Terapias_energeticas
Asunto principal:
Fisiología
/
Terapéutica
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Triglicéridos
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Sangre
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Factor de von Willebrand
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Electroacupuntura
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Colesterol
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Activador de Tejido Plasminógeno
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Ratas Wistar
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Inhibidor 1 de Activador Plasminogénico
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Chinese Acupuncture & Moxibustion
Año:
2006
Tipo del documento:
Article