Bullous hemorrhagic dermatosis due to enoxaparin use in a bullous pemphigoid patient
Asia Pacific Allergy
; (4): 97-101, 2017.
Article
en En
| WPRIM
| ID: wpr-750096
Biblioteca responsable:
WPRO
ABSTRACT
Adverse reactions of subcutaneous low molecular weight heparin or unfractionated heparin could be complications by bleeding, heparin-induced thrombocytopenia, drug-induced liver injury, osteoporosis, and cutaneous reactions. Heparin-induced skin lesions vary from allergic reactions like erythema, urticaria, eczema to intradermal microvascular thrombosis associated with heparin-induced thrombocytopenia. There is a rare cutaneous complication, called bullous hemorrhagic dermatosis. We experienced this rare case of the cutaneous complication caused by enoxaparin. Several tense bullous hemorrhagic lesions occurred after 3 days of enoxaparin in a known bullous pemphigoid patient who had aortic valve replacement surgery with a mechanical prosthesis. The bullous hemorrhagic lesions were regressed after the discontinuation of enoxaparin but recurred after re-administration. The lesions were controlled by the administration of systemic corticosteroid and alternative anticoagulant. To date, less than 20 cases have been reported worldwide. This is the first case of bullous hemorrhagic dermatosis induced by enoxaparin, a low-molecular-weight heparin in Korea. This is also the first case of bullous hemorrhagic dermatosis in a known bullous pemphigoid patient.
Palabras clave
Texto completo:
1
Bases de datos:
WPRIM
Asunto principal:
Osteoporosis
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Válvula Aórtica
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Prótesis e Implantes
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Piel
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Enfermedades de la Piel
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Trombocitopenia
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Trombosis
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Urticaria
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Heparina
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Estimulación Eléctrica Transcutánea del Nervio
País/Región como asunto:
Asia
Idioma:
En
Revista:
Asia Pacific Allergy
Año:
2017
Tipo del documento:
Article