Research progress on and behaviors of poorly soluble Chinese materia medica nanosuspension / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3828-3833, 2018.
Article
en Zh
| WPRIM
| ID: wpr-775410
Biblioteca responsable:
WPRO
ABSTRACT
Nanosuspension (also called nanocrystal suspension or nanocrystal) could significantly enhance the saturated solubility and dissolution of insoluble drugs, and improve their bioavailability by reducing particle size and increasing the specific surface, which could then solve the delivery problems of the poorly soluble active ingredients and effective parts of Chinese materia medica (CMM). Based on the brief summaries of nanosuspension preparation methods, this paper would mainly review the and behaviors of poorly soluble CMM nanosuspension, discuss and analyze its problems, so as to provide reference and thinking for the further study of nanosuspension drug delivery system of poorly soluble CMM and promote the development and perfection of nanosuspension technology in CMM.
Palabras clave
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Medicinas Complementárias:
Homeopatia
Asunto principal:
Tamaño de la Partícula
/
Solubilidad
/
Suspensiones
/
Materia Medica
/
Disponibilidad Biológica
/
Química
/
Sistemas de Liberación de Medicamentos
/
Nanopartículas
/
Medicina Tradicional China
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2018
Tipo del documento:
Article