A New Perspective for Chinese Medicine Intervention for Coronary Artery Disease: Targeting Inflammation / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 3-8, 2019.
Article
en En
| WPRIM
| ID: wpr-776629
Biblioteca responsable:
WPRO
ABSTRACT
Inflammation, which plays a critical role in atherosclerosis and the occurrence of acute cardiovascular events, may be a new target for treatment of coronary artery disease (CAD) to reduce residual cardiovascular risk. Recently, Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease (CANTOS), the largest scale clinical trial that targeted inflammation but not lipids, has affirmed for the first time the inflammatory hypothesis of artherosclerosis and marked the advent of an exciting era of targeting inflammation for the prevention and treatment of cardiovascular diseases. Chinese medicine (CM) is a promising adjuvant therapy for CAD in light of its safety and pleiotropic effect of anti-inflammation, anti-platelet, lipid-regulating, endothelium-protection, microcirculation-improving, etc. In recent years, exploration of anti-inflammatory treatment of CAD with CM has been going on from theory to practice. Taking CANTOS as an example, the design strategy to combine CM and Western medicine to inhibit inflammation were discussed in this paper, which might provide a new perspective for CM intervention on CAD.
Palabras clave
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Asunto principal:
Enfermedad de la Arteria Coronaria
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Usos Terapéuticos
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Quimioterapia
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Medicina Tradicional China
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Antiinflamatorios
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Anticuerpos Monoclonales
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Chinese journal of integrative medicine
Año:
2019
Tipo del documento:
Article