Research progress in mechanism of berberine's antitumor action / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2449-2455, 2021.
Article
en Zh
| WPRIM
| ID: wpr-879146
Biblioteca responsable:
WPRO
ABSTRACT
Malignant tumor, an important factor threatening human life and health, brings huge economic burden to patients. At present, chemoradiotherapy is still the main treatment method for tumor diseases, but there are also great side effects when it plays a therapeutic role. Traditional Chinese medicine in the prevention and treatment of tumor diseases has many advantages such as few side effects, improving the physiological state of patients, and slowing down the side effects of radiotherapy and chemotherapy. Berberine is an effective component of rhizoma coptidis, with a very good antitumor effect. It can inhibit tumor cell proliferation, promote tumor cell apoptosis, inhibit tumor metastasis and angiogenesis, regulate tumor autophagy, reverse multi-drug resistance of tumor, regulate the body immunity, and affect tumor metabolic reprogramming to play its role. Compared with chemical preparations, berberine has a wide range of sources, with high safety and easy access, and has great potential in the prevention and treatment of malignant tumors. In this article, we would mainly review the research progress on the antitumor mechanism of berberine in recent years.
Palabras clave
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
/
Plantas_medicinales
Asunto principal:
Berberina
/
Medicamentos Herbarios Chinos
/
Proliferación Celular
/
Medicina Tradicional China
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2021
Tipo del documento:
Article