Research Progress on Pharmacological Mechanism of Danhong Injection in Treatment of Cardiovascular and Cerebrovascular Diseases / 中国实验方剂学杂志
Chinese Journal of Experimental Traditional Medical Formulae
; (24): 188-196, 2021.
Article
en Zh
| WPRIM
| ID: wpr-906380
Biblioteca responsable:
WPRO
ABSTRACT
Cardiovascular and cerebrovascular diseases are one of the major diseases endangering human health, and its morbidity and mortality are still in the rising stage in our country. Traditional Chinese medicine (TCM) injections play an important role in the prevention and treatment of cardiovascular and cerebrovascular diseases due to their advantages of rapid onset, remarkable curative effect, and convenient use. Among them, Danhong injection (DHI), a Chinese medicine injection for promoting blood circulation and removing blood stasis, is widely used in the clinical treatment of cardio-cerebrovascular diseases. DHI is composed of Salviae Miltiorrhizae Radix et Rhizoma (Danshen in Chinese) and Carthami Flos (Honghua in Chinese), and mainly contains phenolic acids, tanshinones and flavonoids. A large number of studies have shown that DHI has a significant effect in the treatment of ischemic cardio-cerebrovascular diseases, is a representative drug of co-therapy of brain and heart of TCM, its pharmacological effects related to many aspects such as anti-inflammatory, anti-oxidation, anti-coagulation. At the same time, Other studies have also explained the protective effects of DHI on cardiovascular and cerebrovascular diseases through the overall regulation and intervention of multiple targets and pathways. However, DHI has a wide range of clinical applications, there are still many unknown pharmacological effects to be further explored. Therefore, this article summarizes the current researches on the chemical components of DHI, the multi-target and multi-path pharmacological mechanisms of DHI in the treatment of cardiovascular and cerebrovascular diseases, and introduces the latest pharmacological research progress, so as to provide theoretical guidance for clinical rational drug use and subsequent in-depth research.
Texto completo:
1
Bases de datos:
WPRIM
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Tipo de estudio:
Guideline
Idioma:
Zh
Revista:
Chinese Journal of Experimental Traditional Medical Formulae
Año:
2021
Tipo del documento:
Article