The first total synthesis of (+/-)-scopadulin, an antiviral aphidicolane diterpene.
Org Lett
; 3(4): 619-21, 2001 Feb 22.
Article
em En
| MEDLINE
| ID: mdl-11178840
ABSTRACT
[reaction see text] The first total synthesis of (+/-)-scopadulin was accomplished by a stereoselective construction of a quaternary carbon at C-4, conversion of the hindered cyano group to a methyl group via our novel reaction for conversion of primary aliphatic amines into alcohols, and a highly chemo- and stereoselective methylation at C-16.
Buscar no Google
Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Antivirais
/
Plantas Medicinais
/
Diterpenos
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Japão