[Ultrastructural and Ca/P changes of the regenerated bone after mandibular distraction in goats].

ABSTRACT

OBJECTIVE: The aim of this study was to examine the ultra structural and the changes of Ca/P elements of the new bone resulting from mandibular distraction osteogenesis. METHODS: Bilateral mandibular osteotomies were performed in six goats. The mandibles in all animals were lengthened 10 mm using a custom made distracter. Each 2 goats were sacrificed respectively at 2, 4 and 8 weeks after completion of distraction. The distracted callus were harvested and processed for SEM evaluation and Ca/P ratio analysis. RESULTS: The newly generated bone in distraction gap was confirmed by SEM examination, and the contents of Ca, P were found to be elevated with the maturity of distracted callus. CONCLUSION: This study suggested that newly formed bone by mandibular distraction osteogenesis in goats could be remodeled to normal bone.