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Synthesis and biological screening of 7-hydroxy-4-methyl-2H-chromen-2-one, 7-hydroxy-4,5-dimethyl-2H-chromen-2-one and their some derivatives.
Khan, Khalid Mohammed; Saify, Zafar S; Begum, Saeedan; Noor, Fatima; Khan, Muhammad Zarrar; Hayat, Safdar; Choudhary, M Iqbal; Perveen, Shahnaz.
Afiliação
  • Khan KM; HEJ Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. hassaan2@super.net.pk
Nat Prod Res ; 17(2): 115-25, 2003 Apr.
Article em En | MEDLINE | ID: mdl-12713124
7-Hydroxy-4-methyl-2H-chromen-2-one (2), 7-hydroxy-4,5-dimethyl-2H-chromen-2-one (15) and their some derivatives were synthesized for exploring selected biological screening. The compounds 9 and 13 had shown high degree of cytotoxic activity. Three compound 9, 10 and 13 showed high degree of bactericidal activity amongst the present series.
Assuntos
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Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Plantas_medicinales Assunto principal: Benzopiranos / Bactérias Gram-Negativas / Bactérias Gram-Positivas / Fitoterapia / Antibacterianos Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: Nat Prod Res Ano de publicação: 2003 Tipo de documento: Article País de afiliação: Paquistão
Buscar no Google
Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Plantas_medicinales Assunto principal: Benzopiranos / Bactérias Gram-Negativas / Bactérias Gram-Positivas / Fitoterapia / Antibacterianos Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: Nat Prod Res Ano de publicação: 2003 Tipo de documento: Article País de afiliação: Paquistão