Preparation of [131I]lipiodol as a hepatoma therapeutic agent.
Int J Rad Appl Instrum A
; 43(12): 1431-5, 1992 Dec.
Article
em En
| MEDLINE
| ID: mdl-1334953
ABSTRACT
An isotopic exchange method was used to label lipiodol with 131I. The labelling efficiency was > 92.5%, and the radiochemical purity of [131I]lipiodol was above 98% as determined by ITLC. The influencing factors e.g. the heating temperature, reaction time, pH and storage conditions were studied and the optimum conditions were determined. In a pilot study injecting [131I]lipiodol for the treatment of hepatoma, about 70% of hepatoma patients had a response to the treatment with a reduction of alpha-fetoprotein and decrease of hepatoma sizes. The overall median survival was 9 months (range 2-17 months).
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Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Óleo Iodado
/
Carcinoma Hepatocelular
/
Radioisótopos do Iodo
/
Neoplasias Hepáticas
Idioma:
En
Revista:
Int J Rad Appl Instrum A
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
China