Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia.
Intensive Care Med
; 29(11): 2072-6, 2003 Nov.
Article
em En
| MEDLINE
| ID: mdl-14556048
ABSTRACT
OBJECTIVE:
To report the use of tetracyclines for the treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP).DESIGN:
Observational case series.SETTING:
. The Presley Regional Trauma Center located within the Regional Medical Center, Memphis, Tennessee, USA. PATIENTS ANDPARTICIPANTS:
Seven critically ill trauma patients with VAP caused by A. baumannii isolates that were resistant to all antibiotics tested except for doxycycline or minocycline.INTERVENTIONS:
Patients were treated with IV doxycycline or minocycline for an average of 13.5 (range 9-20) days. MEASUREMENTS ANDRESULTS:
Doxycycline or minocycline was successful in six of seven patients.CONCLUSIONS:
Doxycycline or minocycline may be effective for treating multidrug-resistant A. baumannii VAP.
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Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Plantas_medicinales
Assunto principal:
Respiração Artificial
/
Infecções por Acinetobacter
/
Infecção Hospitalar
/
Doxiciclina
/
Pneumonia Bacteriana
/
Acinetobacter baumannii
/
Minociclina
/
Antibacterianos
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Intensive Care Med
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos