Genotoxic effects of cadmium chloride and azadirachtin treated singly and in combination in fish.
Ecotoxicol Environ Saf
; 58(2): 194-201, 2004 Jun.
Article
em En
| MEDLINE
| ID: mdl-15157573
ABSTRACT
The genotoxic effects of cadmium chloride (CdCl(2)) and azadirachtin (Aza) were assessed singly and conjointly in a fish, Oreochromis mossambicus, with endpoints such as chromosome aberrations, abnormal red cell nuclei, abnormal sperm morphology, and protein content (both qualitative and quantitative) of selected tissues, namely, muscle, heart, eye, brain, gill, liver, spleen, and kidney. The primary objectives were, first, to examine if CdCl(2), a common pollutant, and Aza, a natural product of the neem plant used extensively as an 'ecofriendly' agent for many purposes, had any genotoxic effect of their own on nontarget aquatic organisms of economic importance; and second, if Aza could have any ameliorating effect on CdCl(2)-induced genotoxicity in O. mossambicus tissues. As compared with distilled water-treated controls, both CdCl(2) and Aza induced genotoxicity in O. mossambicus, the former in greater quantity than that produced by Aza. However, Cd-induced toxicity in O. mossambicus appeared to be ameliorated to some extent by Aza.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Aberrações Cromossômicas
/
Tilápia
/
Cloreto de Cádmio
/
Limoninas
/
Inseticidas
Tipo de estudo:
Qualitative_research
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Índia