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[Changes of endogenous ouabain in rat serum and certain tissues after exposure to simulated weightlessness].
Liu, Zhao-xia; Gao, Guang-dao; Hu, Yong-jie; Wang, De-sheng; WU, Da-wei; Yuan, Ming; Li, Zhi-li.
Afiliação
  • Liu ZX; Department of Medicine, Xi'an Jiaotong University, Xi'an Shannxi, China. liuzx918@sohu.com
Space Med Med Eng (Beijing) ; 18(2): 94-7, 2005 Apr.
Article em Zh | MEDLINE | ID: mdl-15977385
OBJECTIVE: To investigate the changes of endogenous ouabain (EO) in rat serum and some tissues after exposure to simulated weightlessness and to investigate its possible pathophysiology. METHOD: Male Wistar rats were randomly divided into control group (Con) and 1 week tail-suspension group (TS). Enzyme-linked immunosorbent assay (ELISA) was used to detect the content of EO in serum, hypothalamus, pituitary, adrenal gland, kidney, heart and liver. RESULT: Compared with Con, EO increased significantly in serum, hypothalamus, adrenal gland and kidney after tail suspension (P<0.05). CONCLUSION: Simulated weightlessness induced changes of EO in serum and some tissues, which may have some effects on the regulation of hydro-electrolyte metabolism and cardiovascular functions.
Assuntos
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Base de dados: MEDLINE Assunto principal: Ouabaína / Simulação de Ausência de Peso / Elevação dos Membros Posteriores Idioma: Zh Revista: Space Med Med Eng (Beijing) Ano de publicação: 2005 Tipo de documento: Article País de afiliação: China
Buscar no Google
Base de dados: MEDLINE Assunto principal: Ouabaína / Simulação de Ausência de Peso / Elevação dos Membros Posteriores Idioma: Zh Revista: Space Med Med Eng (Beijing) Ano de publicação: 2005 Tipo de documento: Article País de afiliação: China