[Optimization study on extraction technology of the seed of Ziziphus jujuba var. spinosa by orthogonal design with multi-targets].

OBJECTIVE: To optimize extraction technology of the seed of Ziziphus jujuba var. spinosa with the targets of the total saponin, total jujuboside A and B and total flavonoids. METHOD: In the method of one-way and orthogonal tests, ethanol concentration, amount of ethanol, extraction time and extraction times were the factors in orthogonal test, and each factor with three levels. RESULT: Ethanol concentration and extraction times had significant effect on all the targets, other factors should be selected in accordance with production practice. CONCLUSION: The best extraction technology is to extract for three times with 8 fold ethanol solution (60%), and 1.5 h each time.