Screening of selected Arabian medicinal plant extracts for inhibitory activity against peptidases.
Pharmazie
; 61(4): 359-61, 2006 Apr.
Article
em En
| MEDLINE
| ID: mdl-16649556
ABSTRACT
The methanolic extracts of 20 medicinal plants from the island Soqotra/Yemen were screened with respect to their inhibitory potency against angiotensin converting enzyme (ACE), neutral endopeptidase (NEP) and aminopeptidase N (APN). Eight extracts did not show significant inhibitory activity against the enzymes tested, only Kalanchoe farinacea, Boswellia elongata and Cissus hamaderohensis inhibited all three enzymes. The most active extract was prepared from Kalanchoe farinacea characterized by low IC50 values especially for NEP and APN.
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Base de dados:
MEDLINE
Medicinas Tradicionais:
Medicinas_tradicionales_de_asia
/
Medicina_unani
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
/
Plantas_medicinales
Assunto principal:
Plantas Medicinais
/
Inibidores de Proteases
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
País/Região como assunto:
Asia
Idioma:
En
Revista:
Pharmazie
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Alemanha