[Effect of Herba Epimedii flavone on the osteoblasts metabolism in vitro].
Zhongguo Zhong Yao Za Zhi
; 31(6): 487-90, 2006 Mar.
Article
em Zh
| MEDLINE
| ID: mdl-16722381
ABSTRACT
OBJECTIVE:
To explore the effect of Herba Epimedii flavone (HEF) on the osteoblast metabolism in vitro.METHOD:
Osteoblast were obtained from new born rat calvaria by digestive enzymes. MTF, PNPP and RT-PCR were used to observe the proliferation, activity of ALP and mRNA expression of OPG and RANKL of cultured osteoblasts in vitro.RESULT:
It was found that HEF had the effect on stimulating cell proliferation, activity of ALP and the mRNA expression of OPG of cultured osteoblasts (P < 0.01, P < 0.05).CONCLUSION:
HEF can promote the proliferation, the differentiation and the expression of OPG mRNA of the osteoblasts cultured in vitro.
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Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Osteoblastos
/
Glicoproteínas
/
Receptores do Fator de Necrose Tumoral
/
Receptores Citoplasmáticos e Nucleares
/
Epimedium
/
Flavonas
Idioma:
Zh
Revista:
Zhongguo Zhong Yao Za Zhi
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
China