Relationship among TNF-alpha, sICAM-1, and selenium in presurgical patients with abdominal aortic aneurysms.
Biol Trace Elem Res
; 114(1-3): 31-40, 2006.
Article
em En
| MEDLINE
| ID: mdl-17205985
ABSTRACT
The purpose of our study was to estimate the utility of tumor necrosis factor (TNF), soluble intercellular adhesion molecule-1 (sICAM-1), and selenium (Se) measurements as subsidiary parameters for the diagnosis and differentiation of large aortic abdominal aneurysms (AAAs). The TNF and sICAM-1 levels in AAAs were significantly higher than in the controls. On the contrary, the Se level in AAAs was slightly lower; however, the difference was not significant. sICAM-1 did not correlate with TNF or Se as well as with any physical parameter. TNF was related to body mass index (r = 0.375). A negative correlation was found for Se and the aneurysm's diameter (r = -0.382), especially for the height-adjusted diameter (r = -0.418). The results of the present study do not allow one to count TNF and sICAM-1 as markers of AAA advancement. It was shown for the first time that the level of serum Se is low in ruptured aneurysms, but not in the unruptured AAAs.
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Base de dados:
MEDLINE
Assunto principal:
Selênio
/
Fator de Necrose Tumoral alfa
/
Aneurisma da Aorta Abdominal
/
Molécula 1 de Adesão Intercelular
Idioma:
En
Revista:
Biol Trace Elem Res
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Polônia