A phenylpropanoid glycoside with antioxidant activity from Picria tel-ferae.
Arch Pharm Res
; 30(9): 1062-6, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17958321
ABSTRACT
A phytochemical study on Picria tel-ferae resulted in the isolation of a phenylpropanoid glycoside (1), which was reported for the first time from this plant. The structure of compound 1 was identified as 1-O-3,4-(dihydroxyphenyl)- ethyl-beta-D- apiofuranosyl- (1-->4)-alpha-L-rharmnopyranosyl- (1-->3)-4-O-caffeoyl- beta-D-glucopyranoside on the basis of spectroscopic analyses. In addition, it was found that 1 exhibited a remarkable inhibitory effect on lipid peroxidation initiated by either a free radical [AAPH; 2,2'-azobis-(2-amidinopropane)dihydrochloride] or generated hydroxyl radical (Fe2+/ascorbate). These findings, together with those of previous studies, suggest that P. tel-ferae possesses abundant phenylpropanoid glycosides, and the plant might be used beneficially in the treatment of oxidative stress-related human diseases.
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Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Scrophulariaceae
/
Glicosídeos
/
Antioxidantes
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Arch Pharm Res
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Vietnã