Pancreatic response in healthy dogs fed diets of various fat compositions.
Am J Vet Res
; 70(5): 614-8, 2009 May.
Article
em En
| MEDLINE
| ID: mdl-19405900
ABSTRACT
OBJECTIVE:
To indirectly assess the pancreatic response in healthy dogs that were fed diets of different fat compositions with or without supplemental pancreatic enzymes and medium-chain triglycerides (MCTs). ANIMALS 10 healthy adult dogs. PROCEDURES Dogs were fed 4 diets once in random order at 1-week intervals; food was withheld from the dogs for > or = 12 hours prior to the feeding of each diet. Diets A and B contained 16% and 5% crude fat, respectively; diet C was composed of diet A with pancreatic enzymes; and diet D was composed of diet B with pancreatic enzymes and MCTs. Serum canine trypsin-like immunoreactivity (cTLI) and canine pancreatic lipase immunoreactivity (cPLI) concentrations were measured before (0 hours) and at 1 to 2 and 6 hours after feeding. Serum gastrin concentration was measured at 0 hours and at 5 to 10 minutes and 1 to 2 hours after feeding. A gastrin assay validation study was performed to confirm accuracy of test results in dogs. Data were analyzed by use of a repeated-measures general ANOVA.RESULTS:
Serum cTLI, cPLI, or gastrin concentrations in the dogs did not differ among the different diets fed, among dogs, or over time. When multiple comparisons were analyzed, diet D caused the least amount of measurable pancreatic response, although this difference was not significant. CONCLUSIONS AND CLINICAL RELEVANCE Results did not indicate a significant effect of dietary fat content or addition of supplemental MCT oil or pancreatic enzymes in diets on serum cTLI, cPLI, or gastrin concentrations in healthy dogs.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Pâncreas
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Triglicerídeos
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Gorduras na Dieta
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Suplementos Nutricionais
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Dieta
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Cães
Idioma:
En
Revista:
Am J Vet Res
Ano de publicação:
2009
Tipo de documento:
Article