Hypervitaminosis A inducing intra-hepatic cholestasis--a rare case report.
Exp Mol Pathol
; 88(2): 324-5, 2010 Apr.
Article
em En
| MEDLINE
| ID: mdl-19944093
ABSTRACT
The use of over-the-counter supplements is commonplace in today's health conscious society. We present an unusual case of intrahepatic cholestasis caused by vitamin A intoxication. The patient consumed one Herbalife shake with two multivitamin tablets of the same brand for 12 years. When calculated this equated to more than the recommended daily allowance for vitamin A consumption. Deranged liver function tests were consistent with a cholestatic process. Liver biopsy was obtained and revealed features pathognomonic of vitamin A toxicity, without the usual fibrosis. When the supplements were ceased, his jaundice and alkaline phosphatase completely normalized. This case highlights the importance of health care providers documenting non-prescribed dietary supplements and considering them in the etiology of cholestatic liver disease.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vitamina A
/
Hipervitaminose A
/
Colestase Intra-Hepática
Tipo de estudo:
Etiology_studies
Idioma:
En
Revista:
Exp Mol Pathol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos