Tyrosinase inhibitory effect of quercetin 4'-O-ß-D-glucopyranoside from dried skin of red onion (Allium cepa).
Nat Prod Res
; 25(3): 256-63, 2011 Feb.
Article
em En
| MEDLINE
| ID: mdl-20635304
ABSTRACT
In an effort to find a new whitening agent, we focused our attention on Allium cepa (red onion). Based on biologically guided fractionation using mushroom tyrosinase, quercetin 4'-O-ß-D-glucopyranoside was isolated from the dried skin of A. cepa. Quercetin 4'-O-ß-D-glucopyranoside showed tyrosinase inhibitory activity using L-tyrosine or L-DOPA as a substrate, with IC(50) values of 4.3 and 52.7 µM, respectively. Based on the results obtained, the dried skin of red onion possesses ingredients with potential for skin-whitening cosmetics with anti-tyrosinase activity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quercetina
/
Extratos Vegetais
/
Monofenol Mono-Oxigenase
/
Cebolas
/
Glucosídeos
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Japão