Treatment of murine coccidioidal meningitis with SCH39304.
Antimicrob Agents Chemother
; 34(4): 663-4, 1990 Apr.
Article
em En
| MEDLINE
| ID: mdl-2160794
The triazole SCH39304 was compared with itraconazole and fluconazole for treatment of murine coccidioidal meningitis. Mice were treated for 30 days with 1, 5, 10, or 30 mg of each drug per kg of body weight. Survival and brain tissue counts were measured. At equivalent doses, SCH39304 was more effective than the other triazoles.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Triazóis
/
Coccidioidomicose
/
Meningite
/
Antifúngicos
Idioma:
En
Revista:
Antimicrob Agents Chemother
Ano de publicação:
1990
Tipo de documento:
Article