[Neuroprotective effect of ferulic acid in vitro].

OBJECTIVE: To investigate the neuroprotective effect of ferulic acid on PC12 cells injuries. METHODS: With three models of PC12 cells injured by hypoxia, excitatory amino acids (EAA) and radical, the effect of ferulic acid on injured PC12 cells was observed by MTT assay. RESULTS: Compared with three models, ferulic acid (1-100 micromol/L) could promote cell viability notably (P<0.05 or P<0.01). CONCLUSION: Ferulic acid has notable protective effect on PC12 cells injured by hypoxia, EAA and radical.