Polyphenolic acetylcholinesterase inhibitors from Hopea chinensis.
Planta Med
; 78(10): 1015-9, 2012 Jun.
Article
em En
| MEDLINE
| ID: mdl-22628156
ABSTRACT
Bioassay-guided investigation of the stem bark of Hopea chinensis led to the isolation of two new polyphenols, hopeachinols C(1) and D(2), together with ten known compounds (3-12). Compounds 1 and 2 were determined by extensive analysis of spectroscopic data and computational methods. All of these phytochemicals were tested for acetylcholinesterase inhibitory activity, and five resveratrol-derived compounds (1 and 7-10) exhibited significant activity with their IC50 values ranging from 4.81 to 11.71 µM.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Inibidores da Colinesterase
/
Dipterocarpaceae
/
Polifenóis
Idioma:
En
Revista:
Planta Med
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China