Repigmentation of poliosis after epithelial grafting for vitiligo.
Dermatol Surg
; 39(3 Pt 1): 406-11, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23294472
ABSTRACT
BACKGROUND:
Vitiligo is a disease of color loss from skin and possibly also from hair. The presence of white hair follicles is known to be a bad prognostic sign.OBJECTIVES:
To evaluate the possibility of repigmentation of white hair follicles after epithelial grafting.METHODS:
Patients with recalcitrant vitiligo with loss of hair pigment were treated using Chinese cupping blisters or ultrathin Thiersch grafting after de-epithelialization of vitiliginous patches by dermabrasion. Phototherapy was used afterward to enhance success.RESULTS:
Repigmentation of the skin surface was obtained with as little as 1 to 2 months of phototherapy, as expected, and further follow-up of cases revealed the re-coloring of hair follicles after 4 to 11 months.CONCLUSION:
Re-coloring of poliosis with vitiligo is possible but was unexpected because of the difference in mechanism and signaling required between hair bulb melanization and the surface skin. One likely mechanism to explain this change is that melanocyte stem cells are stimulated and migrate to supply hair bulbs with new mature melanocytes. Epithelial grafting of vitiligo with poliosis in hairy areas should be a treatment of choice when white hair tufts cause cosmetic disfigurement.
Texto completo:
1
Base de dados:
MEDLINE
Medicinas Tradicionais:
Medicinas_tradicionales_de_asia
/
Medicina_china
Assunto principal:
Vitiligo
/
Cor de Cabelo
/
Epitélio
/
Doenças do Cabelo
Tipo de estudo:
Etiology_studies
Idioma:
En
Revista:
Dermatol Surg
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Egito