Antioxidant lignoids from leaves of Ribes nigrum.
Phytochemistry
; 95: 333-40, 2013 Nov.
Article
em En
| MEDLINE
| ID: mdl-23958345
ABSTRACT
Phytochemical investigation of the leaves of Ribes nigrum resulted in the isolation of fourteen compounds, including four 7,7'-epoxylignans, three tetrahydrofuran-type sesquilignans, and a spirocyclic dilignan. Their structures were elucidated by extensive spectroscopic analyses and by chemical transformations. The isolated compounds were evaluated for their antioxidant activities using superoxide anion scavenging assay and DPPH free radical scavenging assay. Ribesin D and ribesin G showed the most potent superoxide anion scavenging activity with EC50 values of 1.24 and 1.12 µM, respectively, and the structure-activity relationship was discussed.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Lignanas
/
Superóxidos
/
Ribes
/
Furanos
/
Antioxidantes
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Japão