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The small molecule indirubin-3'-oxime activates Wnt/ß-catenin signaling and inhibits adipocyte differentiation and obesity.
Choi, O M; Cho, Y-H; Choi, S; Lee, S-H; Seo, S H; Kim, H-Y; Han, G; Min, D S; Park, T; Choi, K Y.
Afiliação
  • Choi OM; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Cho YH; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Choi S; Department of Food and Nutrition, Yonsei University, Seoul, Korea.
  • Lee SH; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Seo SH; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Kim HY; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Han G; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Min DS; 1] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Department of Molecular Biology, College of Natural Science, Pusan National University, Pusan, Korea.
  • Park T; Department of Food and Nutrition, Yonsei University, Seoul, Korea.
  • Choi KY; 1] Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea [2] Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
Int J Obes (Lond) ; 38(8): 1044-52, 2014 Aug.
Article em En | MEDLINE | ID: mdl-24232498
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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Oximas / Fármacos Antiobesidade / Síndrome Metabólica / Adipogenia / Via de Sinalização Wnt / Indóis / Obesidade Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Int J Obes (Lond) Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Oximas / Fármacos Antiobesidade / Síndrome Metabólica / Adipogenia / Via de Sinalização Wnt / Indóis / Obesidade Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Int J Obes (Lond) Ano de publicação: 2014 Tipo de documento: Article