Large current difference in Au-coated vertical silicon nanowire electrode array with functionalization of peptides.
Nanoscale Res Lett
; 8(1): 502, 2013 Nov 26.
Article
em En
| MEDLINE
| ID: mdl-24279451
ABSTRACT
Au-coated vertical silicon nanowire electrode array (VSNEA) was fabricated using a combination of bottom-up and top-down approaches by chemical vapor deposition and complementary metal-oxide-semiconductor process for biomolecule sensing. To verify the feasibility for the detection of biomolecules, Au-coated VSNEA was functionalized using peptides having a fluorescent probe. Cyclic voltammograms of the peptide-functionalized Au-coated VSNEA show a steady-state electrochemical current behavior. Because of the critically small dimension and vertically aligned nature of VSNEA, the current density of Au-coated VSNEA was dramatically higher than that of Au film electrodes. Au-coated VSNEA further showed a large current difference with and without peptides that was nine times more than that of Au film electrodes. These results indicate that Au-coated VSENA is highly effective device to detect peptides compared to conventional thin-film electrodes. Au-coated VSNEA can also be used as a divergent biosensor platform in many applications.
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MEDLINE
Idioma:
En
Revista:
Nanoscale Res Lett
Ano de publicação:
2013
Tipo de documento:
Article