Combination use of ferulic acid, ligustrazine and tetrahydropalmatine inhibits the growth of ectopic endometrial tissue: a multi-target therapy for endometriosis rats.

Tang, Qing; Shang, Fanghong; Wang, Xiaocui; Yang, Yang; Chen, Gang; Chen, Yi; Zhang, Jifen; Xu, Xiaoyu

Tang, Qing; Shang, Fanghong; Wang, Xiaocui; Yang, Yang; Chen, Gang; Chen, Yi; Zhang, Jifen; Xu, Xiaoyu.

Afiliação

Tang Q; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ
Shang F; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ
Wang X; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ
Yang Y; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ
Chen G; Research Center of Medical Chemistry and Chemical Biology, Chongqing Technology and Business University, Chongqing 400067, China.
Chen Y; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ
Zhang J; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ
Xu X; College of Pharmaceutical Sciences & College of Traditional Chinese Medicine, Southwest University, Chongqing 400715, China; Institute of Chinese Medicine, Southwest University, Chongqing 400715, China; Pharmacology of Chinese Materia Medica, The Key Constructing Discipline by the State Administ

J Ethnopharmacol ; 151(3): 1218-1225, 2014 Feb 12.

Article em En | MEDLINE | ID: mdl-24389027

Assuntos

Alcaloides de Berberina/uso terapêutico; Ácidos Cumáricos/uso terapêutico; Endometriose/tratamento farmacológico; Pirazinas/uso terapêutico; Animais; Coristoma/tratamento farmacológico; Coristoma/metabolismo; Quimioterapia Combinada; Endometriose/metabolismo; Endométrio/efeitos dos fármacos; Endométrio/crescimento & desenvolvimento; Endométrio/metabolismo; Estradiol/sangue; Feminino; Hormônio Foliculoestimulante/metabolismo; Hormônio Liberador de Gonadotropina/metabolismo; Proteínas I-kappa B/metabolismo; Interleucina-1beta/metabolismo; Hormônio Luteinizante/metabolismo; Macrófagos Peritoneais/efeitos dos fármacos; Macrófagos Peritoneais/fisiologia; Inibidor de NF-kappaB alfa; Fagocitose/efeitos dos fármacos; Ratos; Ratos Sprague-Dawley; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; An internal control used in Western Blot; CLIA; CMC-Na; COX-2; Carboxymethycellulose (PubChem CID: 6328154); Chemiluminescent Immunoassay; Cycloxygenase-2; DAB; Diaminobenzidine; Diaminobenzidine (PubChem CID: 7071); E(2); ECL; ELISA; ER; ERE; Endometriosis; Enhanced chemiluminescence; Enzyme linked immunosorbent assay; Estradiol; Estradiol (PubChem CID: 5757); Estrogen receptor; Estrogen response element; FA; FBS; FSH; Ferulic acid; Ferulic acid (PubChem CID: 445858); Fetal bovine serum; Follicle-stimulating hormone; GTN; Gestrinone; Gestrinone (PubChem CID: 27812); GnRH; Gonadotropin-releasing hormone; HRP; HSP90; Heat-shock protein 90; Horseradish peroxidase; IL-1ß; IgG; Immunoglobulin G; Inhibitor of nuclear factor-κB; Interleukin-1ß; IκBα; LH; LPS; LZ; Ligustrazine; Ligustrazine (PubChem CID: 14296); Lipopolysaccharide; Lipopolysaccharide (PubChem CID: 11970143); Luteinizing hormone; MTT; NF-κB; NP-40; Nonyl phenoxypolyethoxylethanol; Nuclear transcription factor-κB; PAGE; PBS; PMSF; PVDF; Phenylmethanesulfonyl fluoride; Phosphate buffered saline; Polyacrylamide gel electrophoresis; Polyvinylidene difluoride; RIPA; RPMI; Radio immunoprecipitation assay; Rats; Roswell Park memorial institute; SDS; SP; Sodium Carboxymethycellulose; Sodium dodecyl sulfate; Sodium dodecyl sulfate (PubChem CID: 3423265); Streptavidinperoxidase; TBST; THP; TNF-α; Tetrahydropalmatine; Tetrahydropalmatine (PubChem CID: 72301); Tris-buffered saline and Tween 20; Tumor necrosis factor; ß-actin

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia / Plantas_medicinales Assunto principal: Pirazinas / Alcaloides de Berberina / Ácidos Cumáricos / Endometriose Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2014 Tipo de documento: Article

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