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A new cyclopeptide from endophytic Streptomyces sp. YIM 64018.
Yang, Xueqiong; Yang, Yabin; Peng, Tianfeng; Yang, Fangfang; Zhou, Hao; Zhao, Lixing; Xu, Lihua; Ding, Zhongtao.
Afiliação
  • Yang X; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry ofEducation, School of Chemical Science and Technology,Yunnan University, Kunming 650091, China.
  • Yang Y; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry ofEducation, School of Chemical Science and Technology,Yunnan University, Kunming 650091, China.
  • Peng T; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry ofEducation, School of Chemical Science and Technology,Yunnan University, Kunming 650091, China.
  • Yang F; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry ofEducation, School of Chemical Science and Technology,Yunnan University, Kunming 650091, China.
  • Zhou H; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry ofEducation, School of Chemical Science and Technology,Yunnan University, Kunming 650091, China.
  • Zhao L; Yunnan Institute ofMicrobiology, Yunnan University, Kunming 650091, China.
  • Xu L; Yunnan Institute ofMicrobiology, Yunnan University, Kunming 650091, China.
  • Ding Z; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry ofEducation, School of Chemical Science and Technology,Yunnan University, Kunming 650091, China.
Nat Prod Commun ; 8(12): 1753-4, 2013 Dec.
Article em En | MEDLINE | ID: mdl-24555291
One new cyclopeptide, cyclo(L-Phe-L-Ala-L-Phe-Gly), named as vinaceuline (1) and three known cyclodipeptides, cyclo (Phe-Gly), cyclo (Phe-4-hydroxyl-Pro) and cyclo (Phe-Ile) were isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis. The planar structure of the new compound was assigned on the basis of 1D and 2D NMR spectroscopic techniques, while t he a bsolute configurations of the amino acid residueswere determined by application of the advanced Marfey method. Cyclotetrapeptides are rarely found as Streptomycete metabolites.
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Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Streptomyces / Endófitos Idioma: En Revista: Nat Prod Commun Ano de publicação: 2013 Tipo de documento: Article País de afiliação: China
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Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Streptomyces / Endófitos Idioma: En Revista: Nat Prod Commun Ano de publicação: 2013 Tipo de documento: Article País de afiliação: China