Pharmacokinetic comparisons of five ephedrine alkaloids following oral administration of four different Mahuang-Guizhi herb-pair aqueous extracts ratios in rats.

Wei, Ping; Huo, Hui-ling; Ma, Qing-hai; Li, Han-cheng; Xing, Xue-feng; Tan, Xiao-mei; Luo, Jia-bo

Wei, Ping; Huo, Hui-ling; Ma, Qing-hai; Li, Han-cheng; Xing, Xue-feng; Tan, Xiao-mei; Luo, Jia-bo.

Afiliação

Wei P; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China.
Huo HL; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China.
Ma QH; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China.
Li HC; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China.
Xing XF; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China; Guangdong Province Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou, PR China. Electronic address: xiaoxing0610@163.com.
Tan XM; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China; Guangdong Province Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou, PR China.
Luo JB; School of Chinese Medical Sciences, Southern Medical University, 510515 Guangzhou, PR China; Guangdong Province Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou, PR China. Electronic address: Luojb_smu@163.com.

J Ethnopharmacol ; 155(1): 642-8, 2014 Aug 08.

Article em En | MEDLINE | ID: mdl-24929107

Assuntos

Alcaloides/farmacocinética; Cinnamomum aromaticum/química; Ephedra sinica/química; Administração Oral; Alcaloides/administração & dosagem; Alcaloides/isolamento & purificação; Animais; Disponibilidade Biológica; Cromatografia Líquida de Alta Pressão/métodos; Meia-Vida; Extração Líquido-Líquido; Ratos; Ratos Sprague-Dawley; Espectrometria de Massas em Tandem/métodos

Palavras-chave

Acetonitrile (PubChem CID:6342); Amantadine hydrochloride (PubChem CID:64150); Diethyl ether (PubChem CID:3283); Ephedrine alkaloids; Ephedrine hydrochloride (PubChem CID:65326); Formic acid (PubChem CID:284); MahuangGuizhi herb-pair; Methylene chloride (PubChem CID:6344); Methylephedrine hydrochloride (PubChem CID:198190); Norephedrine hydrochloride (PubChem CID:62943); Norpseudoephedrine hydrochloride (PubChem CID:92920); Pharmacokinetic; Prescription compatibility; Pseudoephedrine hydrochloride (PubChem CID:9581); Sodium carbonate (PubChem CID:10340); UPLCMS/MS

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ephedra sinica / Cinnamomum aromaticum / Alcaloides Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2014 Tipo de documento: Article

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